Banfoxanthone, a new prenylated xanthone from the stem bark of Garcinia ovalifolia (Guttiferaceae)

Bodrix Noudou,Nathalie Mamdem,Celine Djama,Justin Komguem,Augustin Nkengfack,Joseph Mbafor,Jean Wandji

doi:10.7324/japs.2015.50721

Abstract

A detailed chemical investigation of the secondary metabolites from the extract of the stem bark of Garcinia ovalifolia led to the isolation of one new prenylated xanthone named banfoxanthone and five known compounds, namely friedeline, canophyllal, ovalifoloneA, 3-methoxycheffouxanthone, endodesmiadol. Prenylated xanthones isolated from Garcinia ovalifolia and others species of genus Garcinia appear to be useful as chemotaxonomic markers in Garcinia.

Highlights

The genus Garcinia (Guttiferae) is known to produce a variety of biologically active metabolites such as polyisoprenylated benzophenones (Meli Lannang et al, 2010; Gustafson et al, 1992), xanthones (Louh et al, 2008) as well as triterpenoids (Nguyen et al, 2011; Meli Lannang et al, 2008)
A detailed chemical investigation of the secondary metabolites from the extract of the stem bark of Garcinia ovalifolia led to the isolation of one new prenylated xanthone named banfoxanthone and five known compounds, namely friedeline, canophyllal, ovalifoloneA, 3-methoxycheffouxanthone, endodesmiadol
Identification of natural products As a continuation of our previous phytochemical investigation of the stem bark of Garcinia ovalifolia, the present study report the characterization of a new prenylated xanthone namely banfoxanthone (1)

Summary

Introduction

The genus Garcinia (Guttiferae) is known to produce a variety of biologically active metabolites such as polyisoprenylated benzophenones (Meli Lannang et al, 2010; Gustafson et al, 1992), xanthones (Louh et al, 2008) as well as triterpenoids (Nguyen et al, 2011; Meli Lannang et al, 2008). A detailed chemical investigation of the secondary metabolites from the extract of the stem bark of Garcinia ovalifolia led to the isolation of one new prenylated xanthone named banfoxanthone and five known compounds, namely friedeline, canophyllal, ovalifoloneA, 3-methoxycheffouxanthone, endodesmiadol.

Results

Conclusion