Bakteryjne zapalenia opon mózgowo-rdzeniowych u dzieci leczonych w latach 1989–2010 w Wojewódzkim Szpitalu Obserwacyjno-Zakaźnym im. Tadeusza Browicza w Bydgoszczy

Abstract

The aim of the study was to estimate the changes in the clinical course and treatment of meningitis in children hospitalized at the Hospital of Infectious Diseases in Bydgoszcz during the years 1989–2010. Material and methods184 treated children (96 boys and 88 girls) aged from 2 weeks to 18 years, underwent epidemiology, clinical course and treatment of meningitis. ResultsThe etiology detection was 57.1%. Most common pathogens were Neisseria meningitidis (25.00%), Haemophilus influenzae (19.02%) and Streptococcus pneumoniae (8.69%). In the youngest group of patients, the most common causes of meningitis were group B Streptococcus and Salmonella. There were high inflammatory markers in the blood and high pleocytosis in the cerebrospinal fluid. Top rates of these indexes, as well as a serious course of the disease, were observed in meningitis due to Streptococcus pneumoniae. Conclusions1.Throughout the analyzed time a significant decrease in meningitis incidence was observed.2.The etiological changes of meningitis through the years reflect the introduction of active immunoprophylaxis and suggest a possibility of the occurrence of meningitis due to non-vaccination strains.3.An increase in the incidence of meningitis due to Streptococcus pneumoniae and Neisseria meningitidis C as well as its serious clinical course signalizes the need of vaccination recommendation.4.Inflammation markers indicate a correlation with the patient's clinical condition and the dynamism of the illness process.5.Higher antibiotic therapy efficacy results in shorter meningitis treatment duration.