Abstract

<div>A dengue tem se tornado um fenômeno anual em Nova Deli. Cada surto é distinto do outro por meio de características clínicas,</div><div>morbidade e mortalidade. O objetivo deste estudo é analisar o perfil clínico e laboratorial da dengue na epidemia de 2008 em</div><div>uma instituição de atendimento terciário na Índia. Foram analisados os prontuários de todos os casos diagnosticados como</div><div>dengue durante o período de julho de 2008 a dezembro de 2008 em um hospital terciário. O estudo consistiu de 103 pacientes:</div><div>63% do sexo masculino; idade média de 22 anos. Um terço dos pacientes apresentavam alguma manifestação cutânea, 30</div><div>pacientes tinham hepatomegalia e 8 tinham esplenomegalia. De características incomuns, 2 pacientes tiveram convulsões, 1</div><div>tinha poliserosite e 1 tinha insuficiência hepática aguda. Um aumento da SGPT (>60 U/L) foi observado em 60% dos casos. Vinte</div><div>e três pacientes tiveram uma contagem de plaquetas inferior a 20.000/mm3. Não houve mortes. Este surto envolveu indivíduos</div><div>de faixa etária economicamente produtiva. O surto também foi caracterizado pelo alto índice de comprometimento hepático.</div>

Highlights

  • Dengue fever is an arboviral disease transmitted byAedes aegyptimosquito caused by four serotypes of dengue virus, DEN 1-4

  • Several epidemics of Dengue Hemorrhagic Fever (DHF)/Dengue Shock syndrome (DSS) have occurred in India in several states over the last five decades, the major ones in the last two decades in Delhi occurred in 1988, 1996 and 2003.1,2,3 Cases of dengue are reported every year with cases peaking in the months of September to November when conditions are ideal for disease transmission by the vector

  • It has been seen that the clinical manifestations, morbidity and mortality vary from epidemic to epidemic and there are recent reports of more unusual features accompanying the dengue fever.[4]

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Summary

Introduction

Dengue fever is an arboviral disease transmitted byAedes aegyptimosquito caused by four serotypes of dengue virus, DEN 1-4. Dengue fever is endemic in many parts of North India with cases reported every year. Dengue Shock syndrome (DSS) and Dengue Hemorrhagic Fever (DHF) arethe more severe forms of the disease with considerable higher mortality and morbidity. Several epidemics of DHF/DSS have occurred in India in several states over the last five decades, the major ones in the last two decades in Delhi occurred in 1988, 1996 and 2003.1,2,3 Cases of dengue are reported every year with cases peaking in the months of September to November when conditions are ideal for disease transmission by the vector. It has been seen that the clinical manifestations, morbidity and mortality vary from epidemic to epidemic and there are recent reports of more unusual features accompanying the dengue fever.[4] The current report is a study of all cases

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