Abstract
Strains of Bacillus subtilis 168 deficient in glucosylated teichoic acid vary in their resistance to bacteriophage infection. Although glucosylated teichoic acid is important for bacteriophage attachment, the results demonstrate that alternate receptor sites exist. Non-glucosylated cell wall mutants could be assigned to specific classes (gtaA, gtaB, gtaC) by their pattern of resistance to three closely related bacteriophages (phi25, phie, SP82). In addition to glucosylation, the type of teichoic acid was also important for bacteriophage attachment. B. subtilis strains 168 and W23 have different teichoic acids in their cell walls and have varied susceptibilities to bacteriophage infection. Transfer of bacteriophage resistance from strain W23 into a derivative of strain 168 was accomplished. The resistant bacteria obtained were imparied in their ability to adsorb bacteriophage and in their capacity to be transfected by bacteriophage deoxyribonucleic acid.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
