Abstract
Bacteriophages lytic for Escherichia coli strains were isolated from two lots of oral poliomyelitis vaccine. From one ultracentrifuged sample bacteriophages of four different plaque patterns were demonstrable with E. coli C 3000 (2·8 × 10 2 PFU/ml) and E. coli Φ (1·1 × 10 2 PFU/ml) as indicator strains. The phage contamination of virus vaccines and its possible consequences need further investigations.
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