Bacteriophage as Therapeutic Strategy Against Pathogenic Vibrio

Abstract

Disease outbreaks frequently impede aquaculture’s expanded expansion. Bacterial infections are one of the main issues among them. Antibiotics are frequently used in the treatment of bacterial diseases in aquaculture. Bacteriologists must create alternative control agents due to the emergence of bacteria that are resistant to standard antibiotics and bactericides as well as their possible adverse effects on the environment and human health. Therefore, new bacterial disease control methods are required. Bacteriophage therapy is thus one of the tactics. Bacteriophages, viruses that can only infect and kill highly particular types of bacteria, are potential agents with no known harmful impacts on the environment or human health. Numerous bacteriophages have been discovered to combat various fish pathogenic bacteria, and numerous studies have demonstrated how effectively they may control the spread of disease in both closed and open environments. This chapter contains details on potential bacteriophages that can fight off illnesses brought on by fish pathogenic bacteria. Bacteriophages must be bactericidal, highly specific to their host, accurately identified, free of virulence factors and stable in a variety of environmental conditions for bacteriophage therapy to be successful. With these qualities, the phage may be useful for treating vibriosis in aquaculture.