Bacteriophage: A New Hope for the Control of Antibiotic-Resistant Bacteria

Abstract

Discovery of penicillin has replaced all the traditional chemotherapeutics and increased dependency on it for limiting infections. Dependency of medical world on the antibiotics has been traded off by drug-resistant bacteria. Emergence of drug-resistant bacteria is a consequence of abused medical practices, which led us toward the edge of pre-antibiotic era. Modern medicine is severely threatened by the multiple drug-resistant (MDR) bacteria, due to limitations of potent new antibiotics. Although modern medicine has adopted many new alternatives, but they have not earned success like lifesaving antibiotics due to poor pharmacokinetics. Bacteriophage therapy has drawn the attention of researchers, due to their host specificity and self-replicating, effeciently economical, and eco-friendly properties. Infact, phage therapy was in use since the twentieth century, the discovery of antibiotic and lack of information about phage therapy pharmacokinetics caused a decline in the use of phage therapy. Herein, we have focused a torch of light on phage therapy.