Abstract
Wound infection following major oral cancer sugery is a common complication which leads to a significant morbidity and prolonged hospitalization. Bacteria of wound discharges was studied in 25 patients after major oral cancer surgery from Jan. 1990 to Jan. 1995 in Kaohsiung CGMH, polymicrobials were identified in 92% (23/25) of cases. Among aerobic culture, Streptococcus are the most common, especially Streptococcus viridans species (15/25), followed by Pseudomonas aeruginosa (9/25), Enterococcus (8/25) and Escherichia coli (6/25). Among anaerobic culture, Bacteroid melaninogenicus (9/25) and Bacteroid species (6/25) are the most common pathogens. Proper selection of antibiotics for perioperative use is still important for the prophylactic option. The priority of treatment of infected wound is adequate open drainage by suture removal and accompanied by broad spectrum antibiotics coverage. Sensitivity test of the bacteria shows penicillin group (Ticarcillin, Pipril, Ampicillin), aminoglycoside group (Amikacin, Netilmicin, Gentamicin) or 3° Cephalosporin are effective. Clindamycin and metronidazole groups are selected for combat anaerobic bacteroids. There is no septic mortality in our series.
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