Abstract

To retrospectively analyze the bacteriological spectrum and drug susceptibility of pus flora from abdominal traumatic patients with severe intra-abdominal infection. A total of 41 severe intra-abdominal infected patients with abdominal trauma were recruited to collect 123 abdominal pus specimens. And the results of laboratory microbiology and drug sensitivity were analyzed with the WHONET 5.4 software. A total of 297 strains of bacteria were isolated at (7.2 ± 2.3) strains for each patient. Gram-positive bacteria accounted for 44.1% (131/297) , Gram-negative bacteria 55.2% (164/297) and fungi 0.7% (2/297). The top five isolates were Escherichia coli, Staphylococcus aureus, Klebsiella pneumonia, Enterococcus faecalis and Pseudomonas aeruginosa. Those antibiotics highly sensitive (>90%) to Escherichia coli included cefoperazone (91%), imipenem (98%); highly sensitive to Gram-positive cocci included teicoplanin (100%) and linezolid (100%). Staphylococcus aureus was 100% sensitive to vancomycin. The agents with a high susceptibility to Klebsiella pneumonia included imipenem (100%) and amikacin (79%). Ciprofloxacin (90%) had the highest sensitivity to Pseudomonas aeruginosa. The predominant bacteria of causing severe intra-abdominal infection of traumatic patients is Gram-negative bacteria, but the infection of Gram-positive bacteria, especially the ratio of Staphylococcus aureus infection is also comparatively high. Cefoperazone, ciprofloxacin, imipenem, vancomycin, teicoplanin and linezolid have higher antibacterial activity.

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