Bacteriological profile and antibiotic susceptibility pattern of neonatal septicaemia-a prospective study

Abstract

Background: Neonatal sepsis is one of the major cause of mortality and morbidity Globally, objective of this prospective study was to evaluate the microorganisms profile involved in neonatal septicemia and their antibiotic susceptibility. Methods: This prospective study conducted in neonate admitted to Mahatma Gandhi Mission Medical College and Hospital Aurangabad Maharashtra in NICU, from June 2021 to May 31, 2022. Data was analysed by percentages of each antibiotic used. And which organism was responsible for neonatal sepsis. Results: In this study we have found that high bacterial prevalence of Klebsiella at 36%, Enterococci at 23.5 and staph aureus at 19.8% in neonatal sepsis. While the antibiotics most used was Piperacillin and tazobactam, meropenam, colistin, cefotaxime, amikacin. In our setting we found that bacteria are still sensitive to third generation cephlosporings. Conclusions: From our study we can conclude that, in our tertiary care hospital Klebsiella is major cause of neonatal sepsis, along with-it sensitivity with effectiveness of cephalosporin.