Abstract
A rapid and simple method for the evaluation of antiseptic substances, using animal leukocytes is described. A comparison between the bactericidal and leukocidal concentrations of a given compound yields a relative measure of the toxicity of the test substance, and under the test condition, only gentian violet, Chlorox, and Isodine, of fifteen compounds tested, show a lower toxicity to phagocytes than to bacteria. The method described should prove valuable for small laboratories or for rapid evaluation of new compounds, although values so obtained cannot be the sole criterion for the determination of the effectiveness or usefulness of a wound disinfectant.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Journal of Pharmaceutical Sciences (Scientific Edition)
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
