Bacterial Profile And Sensitivity Test Overview From Endotracheal Tube Aspirate Specimens From Confirmed Positive For Covid-19 Patients In Special Isolation Room Dr. Soetomo Hospital Surabaya

Abstract

Background: Patients with COVID-19 who are treated in the Special Isolation Room (RIK) 1 are patients who experience respiratory failure and therefore use mechanical ventilation. The use of mechanical ventilation has a very high risk of infection in the respiratory tract accompanied by increased morbidity, especially in Multidrug Resistant (MDR) microorganism infections. This study aims to determine the profile of bacteria and the description of their sensitivity to antibiotics from Endotracheal Tube (ETT) aspirate specimens in COVID-19 patients at RIK 1 RSUD Dr. Soetomo Surabaya. Methods: This study is a descriptive study of secondary data on aerobic culture of ETT aspirate specimens of COVID-19 patients treated at RIK 1 RSUD Dr. Soetomo Surabaya for the period March 2020-December 2020. Results: Collected as many as 107 data from bacterial culture and sensitivity test to antibiotics. Gram negative bacteria were the most common microorganisms, namely 71 (59.6%), while Gram positive bacteria were 32 (26.9%). Acinetobacter baumannii was the most common Gram negative bacteria, namely 27 (22.7%). Then 12 (10.1%) Klebsiella pneumoniae ESBL and 11 (9.2%) Klebsiella pneumoniae. From the group of Gram positive bacteria the most were Streptococcus viridans 8 (6.7%), Corynebacterium striatum and Staphylococcus aureus each with 3 (2.5%). MRSA bacteria were found as many as 2 (1.7%). The antibiotic that has the highest sensitivity to Acinetobacter baumannii, Klebsiella pneumoniae and Klebsiella pneumoniae ESBL is Amikacin. While the 2nd, MRSA found were still sensitive to Linezolid, Rifampicin, Quinupristin dalfopristin, Tetracyclin, Teicoplanin and Vancomycin. Conclusion: Acinetobacter baumannii was the most common microorganism isolated from ETT aspirate specimens in RIK 1 COVID-19 patients at Dr. Soetomo Surabaya and has the highest sensitivity to Amikacin antibiotics.