Abstract
BackgroundUrinary tract infection (UTI) is a common health problem among pregnant women. Proper investigation and prompt treatment are needed to prevent serious life threatening condition and morbidity due to urinary tract infection that can occur in pregnant women. Recent report in Addis Ababa, Ethiopia indicated the prevalence of UTI in pregnant women was 11.6 % and Gram negative bacteria was the predominant isolates and showed multi drug resistance. This study aimed to assess bacterial profile that causes urinary tract infection and their antimicrobial susceptibility pattern among pregnant women visiting antenatal clinic at University of Gondar Teaching Hospital, Northwest Ethiopia.MethodsA cross-sectional study was conducted at University of Gondar Teaching Hospital from March 22 to April 30, 2011. Mid stream urine samples were collected and inoculated into Cystine Lactose Electrolyte Deficient medium (CLED). Colony counts yielding bacterial growth of 105/ml of urine or more of pure isolates were regarded as significant bacteriuria for infection. Colony from CLED was sub cultured onto MacConkey agar and blood agar plates. Identification was done using cultural characteristics and a series of biochemical tests. A standard method of agar disc diffusion susceptibility testing method was used to determine susceptibility patterns of the isolates.ResultsThe overall prevalence of UTI in pregnant women was 10.4 %. The predominant bacterial pathogens were Escherichia coli 47.5 % followed by coagulase-negative staphylococci 22.5 %, Staphylococcus aureus 10 %, and Klebsiella pneumoniae 10 %. Gram negative isolates were resulted low susceptibility to co-trimoxazole (51.9 %) and tetracycline (40.7 %) whereas Gram positive showed susceptibility to ceftriaxon (84.6 %) and amoxicillin–clavulanic acid (92.3 %). Multiple drug resistance (resistance to two or more drugs) was observed in 95 % of the isolates.ConclusionSignificant bacteriuria was observed in asymptomatic pregnant women. Periodic studies are recommended to check the outcome of asymptomatic bacteriuria and also monitor any changes in the susceptibility patterns of urinary tract pathogens in pregnant women.
Highlights
Urinary tract infection (UTI) is a common health problem among pregnant women
Urinary tract infection accounts for a significant part of the work load in clinical microbiology laboratories and enteric bacteria remained the most frequent cause of UTI, the distribution of pathogens that cause UTI is changing [2]
Urinary tract infection is a common health problem among pregnant women [1]. This usually begins in week 6 and peaks during weeks 22 to 24 of pregnancy due to a number of factors including urethral dilatation, increased bladder volume and decreased bladder tone, along with decreased urethral tone which contributes to increased urinary stasis and ureterovesical reflux and up to 70 % of pregnant women develop glycosuria, which encourages bacterial growth in the urine [3]
Summary
Urinary tract infection (UTI) is a common health problem among pregnant women. Urinary tract infection accounts for a significant part of the work load in clinical microbiology laboratories and enteric bacteria remained the most frequent cause of UTI, the distribution of pathogens that cause UTI is changing [2]. Urinary tract infection is a common health problem among pregnant women [1]. This usually begins in week 6 and peaks during weeks 22 to 24 of pregnancy due to a number of factors including urethral dilatation, increased bladder volume and decreased bladder tone, along with decreased urethral tone which contributes to increased urinary stasis and ureterovesical reflux and up to 70 % of pregnant women develop glycosuria, which encourages bacterial growth in the urine [3]
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
