Abstract
Introduction and Objectives: Urinary tract infection (UTI) is one of the most common infections in childhood. The objective of our study was to ascertain the commonest organisms causing UTI in children and their ABST patterns. The study was carried out in a Teaching Hospital in Sri Lanka. Methods: Data was collected from children who were confirmed to have UTI by positive urine culture (>105 bacteria/ml urine) between July-December 2015. The clinical presentation, presence of predisposing factors and reports of urine culture and the antibiotic susceptibility patterns were analysed. Results: Coliforms were found to be the commonest organism followed by Enterococcus spp. Nitrofurantoin showed the highest sensitivity of the tested antibiotics against both coliforms and the enterococcus groups. However the sensitivity to most of the antibiotics showed a reduction from previously recorded values in studies done in Sri Lanka. Conclusions: The authors emphasize the need for regular revision of the list of organisms causing UTI and the antibiotic sensitivity to improve the treatment of childhood UTI with the ideal antibiotic.
Highlights
Introduction and ObjectivesUrinary tract infection (UTI) is one of the most common infections in childhood
In children presenting with UTI, 30-40% have underlying vesico-ureteric reflux (VUR), while other congenital anomalies like posterior urethral valves, pelvi-ureteric junction obstruction, ureteroceles and duplex systems are encountered less frequently.[3]
Features are often non-specific and it is recommended to perform a semiquantitative urine culture to confirm the diagnosis in children with suspected UTI.[5]
Summary
Introduction and ObjectivesUrinary tract infection (UTI) is one of the most common infections in childhood. Fever, increased frequency, straining on micturition, diarrhoea and offensive urine are the common presentations of childhood UTI.[3,4] Features are often non-specific and it is recommended to perform a semiquantitative urine culture to confirm the diagnosis in children with suspected UTI.[5] Management of UTI is with either oral or parenteral antibiotics depending on the clinical need.[6] The initial choice of antibiotics is decided on available clinical guidelines, with availability, cost and personal preferences playing a secondary role.[7] Clinical guidelines are available in both Sri Lankan and international contexts and provide guidance for initial antibiotic choice.[8,9,10] As the treatment of the acute episode is of utmost importance, the correct choice of initial antibiotic should be based on local and timely information of the responsible organisms and their ABST pattern. Non-response to initial treatment requires a change of antibiotic guided by the ABS results and/or further investigation
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
