Abstract

Bacterial nanocellulose membranes as potential chronic wound dressing: influence of alternative culture media on nanofiber diameter - a brief review

Highlights

  • The skin is the largest organ of the human body, and it is composed of two distinct layers: the epidermis and the dermis

  • The predominance of kombucha-like can be associated with the popularity of the drink and the simplicity of the process, what can be compared to a static production of bacterial nanocellulose (BNC)

  • On account of the economic and social impact of chronic wounds worldwide, aligning nanoscience and biomaterials can lead to alternatives to this issue

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Summary

Introduction

The skin is the largest organ of the human body, and it is composed of two distinct layers: the epidermis (external part) and the dermis (internal part). Its major function is the protection of adjacent tissues, in which the skin acts as a mechanical barrier against impacts and humidity loss, besides serving as a chemical barrier that promotes an acidic layer to suppress bacterial growth (BARANOSKI et al, 2016; SUSSMAN; BATES-JENSEN, 2012). The exact mechanisms that lead to an improper wound healing process are not well defined nowadays, the two main factors are chronic diseases and aging (KEVIN; VAN DEN KERKHOF; JIMENEZ, 2016). When it takes more than three months for the wound to heal, and the healing process is not ordered, it is defined as a chronic wound (KORTING; SCHÖLLMANN; WHITE, 2011)

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