Abstract
to evaluate the use of a bacterial cellulose biopolymer film and gel dressing in the treatment of patients with ischemic wounds submitted to lower limb revascularization. we conducted a randomized clinical trial in the Angiology and Vascular Surgery outpatient clinic of the Clinics Hospital of the Federal University of Pernambuco, between January 2017 and December 2018. We followed 24 patients after lower limb revascularization, divided into two groups: Experimental, treated with bacterial cellulose biopolymer film and gel, and Control, treated with essential fatty acids. Patients attended weekly appointments to change dressings and had their wound healing processes evaluated over a period of 90 days. the reduction of the ischemic wounds' areas after 30 days was 4.3cm2 (55%) on average for the experimental group, and the 5.5cm2 (48.5%) for the control group (p>0.05). The complete healing rate at 90 days was 34.8%, 50% in the experimental group and 18.2% in the control group (p=0.053). the bacterial cellulose biopolymer film associated with gel can be used as a dressing in the treatment of ischemic wounds of patients undergoing revascularization of the lower limbs.
Highlights
The most severe manifestation of lower limbs (LL) peripheral obstructive arterial disease (PAD) is the ischemic wound (IW)
Most patients with IW are candidates for open or endovascular arterial revascularization surgery, which aims to restore blood flow to the lower limb and avoid major amputations, which cause a significant deterioration in quality of life and increased mortality
The aim of this study is to evaluate the use of cellulose biopolymer film with associated gel (CBFG) in the treatment of IW after revascularization of the lower limbs[4,5,6,7,8,9,10]
Summary
The most severe manifestation of lower limbs (LL) peripheral obstructive arterial disease (PAD) is the ischemic wound (IW). It occurs most often in the foot and leg and is associated with a high risk of limb loss[1]. In addition to arterial revascularization surgery, patients with IW often undergo surgical debridement and minor amputations. These procedures are performed after revascularization surgeries and aim to promote the removal of devitalized and infected tissues, and to facilitate the healing process[1,2,3]. There is no standardization as to the material used in the dressings of such wounds, and several protocols are used[1,2,3]
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