Abstract

A method is described for the preparation of bacterial cell walls by filtration. In addition to its applications in laboratory-scale work, the process is potentially useful for the isolation of purified cell walls for the production of vaccines, antigens and antibodies for diagnostic purposes or use as general laboratory reagents, and as starting materials for the preparation of muramylpeptides active as adjuvants and anti-cancer agents. Factors affecting the rate of processing are assessed and suggestions for shortening the process time or scaling up the batch size are presented.

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