Abstract
There is a paucity of information on enteric fever in Sri Lanka. This laboratory-based study aimed to identify the causative agent and demographic profile of patients with blood culture confirmed enteric fever at a private hospital in Colombo between February 2011 and November 2012. There were 100 isolates, S. Paratyphi A (n=92) and S. Typhi (n=8). Eighty-three patients were below 40 years. Antimicrobial resistance was seen to ciprofloxacin and azithromycin. If the emergence of S. Paratyphi A as an important cause of enteric fever is confirmed by further studies, the development of a bivalent vaccine effective against both typhoid and paratyphoid fever will be required for prevention of enteric fever.
Highlights
Enteric fever is endemic in most developing countries and includes typhoid and paratyphoid fevers caused by Salmonella Typhi
Blood culture positive enteric fever patients presenting to the hospital between February 2011 and November 2012 were identified from laboratory records and patient records were retrieved for analysis
A total of 100 blood culture positive enteric fever patients were included in the study, 92 patients with paratyphoid fever and 8 patients with typhoid fever
Summary
Typhi) and Salmonella Paratyphi (A, B and C) The global estimated cases of typhoid fever in 2000 was 22 million with 2.2 million deaths while that of paratyphoid fever was 5.5 million with no deaths [1]. Notably Asia and South Asia, the proportion of cases due to S. Paratyphi A are increasing [2,3]
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