Abstract
Background: Tonsillitis is an inflammation of the tonsils due to either viruses or bacteria. Here, we report the bacteria patterns on the tonsillar surface and tonsillar core tissue among patients scheduled for tonsillectomy at Bugando Medical Centre (BMC), Mwanza Tanzania. Methods: The study included 120 patients planned for tonsillectomy between April and July 2019. Swab samples from tonsillar surface pre-tonsillectomy and core post-tonsillectomy were collected. Culture was performed following the microbiology laboratory standard operating procedures. Data analysis was completed using STATA version 13, as per the study objectives. Results: The slight majority of participants were males (73; 60.83%) with median age of 6 years (interquartile range 4–11). The proportion of positive culture growth was higher on the surface than in core swab samples: 65 (54.2%) vs. 42 (35.0%), p = 0.003. The commonest bacterial pathogen detected from the surface and core were S. aureus in 29 (40.3%) and 22 (51.2%) participants, followed by S. pyogenes in 17 (23.6%) and 11 (25.6%), respectively. Methicillin-resistant Staphylococcus aureus (MRSA) was observed in 20/51 (39%) of isolates. Streptococcus pyogenes resistance to macrolides ranged from 8.3% for core isolates to 35.3% for surface isolates. Features suggestive of tonsillitis on histology were reported in 83 (73.5%) samples. Conclusion: More than two-thirds of patients undergoing tonsillectomy had a positive culture for possible bacterial pathogens. Staphylococcus aureus and Streptococcus pyogenes were the predominant bacteria detected with more than one third of Staphylococcus aureus being MRSA. More studies to investigate the treatment outcome of these patients are highly recommended.
Highlights
Tonsillectomy is one of the most frequently performed otolaryngological operation worldwide [1]
The primary aim of this study was to determine patterns of Gram-positive bacteria on the tonsillar surface pre tonsillectomy and tonsillar core tissue post tonsillectomy, among patients scheduled for tonsillectomy at Bugando Medical Centre (BMC), Mwanza, Tanzania, in order to obtain data to guide the empirical treatment of tonsillitis
A total of 27 (38.5%) tissues had a positive growth of possible pathogenic bacteria on both surface and core swabs
Summary
Tonsillectomy is one of the most frequently performed otolaryngological operation worldwide [1]. With at least five or more attack episodes in a year, obstructive sleep apnea and peritonsillar abscess, is indicated in patients with adenotonsillar hypertrophy [4]. Recurrent acute tonsillitis is mainly associated with bacterial and/or viral infection of the tonsillar crypts or parenchyma, and is characterized by sore throat, fever, odynophagia, and leukocytosis, accompanied by congested tonsils with or without enlargement and tender jugulodigastric lymph nodes. We report the bacteria patterns on the tonsillar surface and tonsillar core tissue among patients scheduled for tonsillectomy at Bugando Medical Centre (BMC), Mwanza Tanzania. Methods: The study included 120 patients planned for tonsillectomy between April and July 2019. The proportion of positive culture growth was higher on the surface than in core swab samples: 65 (54.2%)
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