Abstract
Background: Bloodstream infections are an emerging cause of signicant morbidity and mortality in critically ill COVID-19 patients. The present study was designed to evaluate the incidence of BSI and to identify its causative agents in critically ill Covid positive patients to provide targeted therapy to improve the outcome in such patients. This retrospective observational study was conducted at Tejas Microdiagnostics during 30Material and method: April 2021 to 30 June 2021. A total of 126 Covid positive patients requiring admission in SRN Hospital, Prayagraj were included. Blood specimen collected in FA and FAN bottles were sent for culture and antibiogram to Tejas Microdiagnostics within eight hours of admission. Blood culture of 89 (70%) patients was positive while 37 (30%) patients did not show any growth.Results: Bacterial growth was identied in 65 (73.04%) cases while fungi were isolated in 24 (26.96%) cases. Acinatobacter was identied in single patient. Klebsiella pneumoneae (19.23%) and Staphylococcus aureus (15.38%) were the predominant gram negative and gram positive aerobes while Fusobacterium (46.15%) and Peptococcus (15.38%) was gram negative and gram positive anaerobes. Mortality was observed in 21% cases. Our study emphasizes that blood stream infectionsConclusion: appeared to be the signicant cause of morbidity and mortality in Covid positive patients. The reason of infections can be the wide spread use of empirical antibiotics and steroids which may increased the risk of antibiotic drug resistance and treatment failure. Therefore to reduce morbidity and mortality we have to ensure rapid Isolation and species identication in such patients.
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