Abstract
HP0062 is an 86 residue hypothetical protein from Helicobacter pylori strain 26695. HP0062 was identified ESAT-6/WXG100 superfamily protein based on structure and sequence alignment and also contains leucine zipper domain sequence. Here, we report the sequence-specific backbone resonance assignment of HP0062. About 97.7% of all <TEX>$^1H_N,\;^{15}N,\;^{13}C_{\alpha},\;^{13}C_{\beta}\;and\;^{13}C=O$</TEX> resonances were assigned unambiguously. We could predict the secondary structure of HP0062 by analyzing the deviation of the <TEX>$^{13}C_{alpha}\;and\;^{13}C_{\beta}$</TEX> chemical shifts from their respective random coil values. Secondary structure prediction shows that HP0062 consist of two <TEX>${\alpha}$</TEX>-helices. This study is a prerequisite for determining the solution structure of HP0062 and can be used for the study on interaction between HP0062 and DNA and other Helicobacter pylori proteins.
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