Back cover story: Eur. J. Immunol. 1'18

Abstract

European Journal of ImmunologyVolume 48, Issue 1 Back CoverFree Access Back cover story: Eur. J. Immunol. 1'18 First published: 10 January 2018 https://doi.org/10.1002/eji.201870018AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Graphical Abstract Our back cover features the immunohistology of a lung from a C57BL/6 mouse re-challenged with influenza A virus (IAV). In the center panel, the juxtaposition of lung epithelial cells (stained with anti-E-cadherin, red) and inflammatory cells (anti-CD103, green), including migrating DCs and intraepithelial T-cells, is displayed in addition to nuclear staining (blue). The image is taken from Yoshizawa et al. (pp. 128–150), where the authors show that airway epithelia and adjacent lamina propria locales, not iBALT, represent microenvironments for tissue resident memory T-cell generation. Transcriptional profiling reveals differences in activation, attenuation and adhesion pathways amongst polyclonal resident effector and memory T-cells based on an TCR-pMHC encounter involving two immunodominant IAV epitopes. Volume48, Issue1January 2018 RelatedInformation