Abstract
DOI: 10.1002/pmic.201700465 Immunopeptidomic profiling of biopsies from HLA-A2-positive triple negative breast cancer patients identifies a high number of shared tumor-associated HLA-A2 peptide antigens. Calculation of the average protein tumor-associated cohort coverage (aTaCC) shortlists antigens that are presented with higher abundance in tumor tissue than in normal tissue and may prioritize the selection of target antigens for immunotherapy. This is reported in article number 1700465 by Ternette et al.
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