Abstract
ON THE BACK COVER: Schematic illustration that shows: In pathology, Tau (in green) targets the tyrosine kinase Fyn (yellow) to dendritic spines, where it phosphorylates subunit NR2b of the NMDA receptor (NMDAR, dark blue at the postsynaptic density), which leads to recruitment of PSD‐95 (light blue) and formation of NMDAR/PSD95 complexes. Aβ oligomers (orange, extracellular) induce excitotoxicity by signalling through NMDAR/PSD95 complexes.Credit: Alison Carlisle, Queensland Brain Institute, The University of Queensland.image
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