Abstract

A facile covalent reaction-induced assembly is introduced to construct monodispersed dipeptide-based nanospheres with excellent biocompatibility. Interestingly, such assembled nanospheres can serve as intrinsic photosensitizers to convert O2 to singlet oxygen (1O2) and exhibit red autofluorescence. Thus, photodynamic therapy in vitro can be achieved effectively. This versatile strategy to fabricate potential intrinsic photosensitizers may be extended to other biomolecules containing primary amine groups. More information can be found in the Communication by J. Li et al. on page 6477 ff.

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