Abstract
DOI: 10.1002/elps.201700273 The cover picture shows chiral separations of racemic analytes on a new single-urea-bound β-cyclodextrin chiral stationary phase by HPLC. This new CSP was prepared through the Staudinger reaction of β-cyclodextrin derivative and 3-aminopropyl silica gel under CO2 atmosphere. It exhibited good separation performance for 33 analytes using normal-phase HPLC conditions. Effects of structure of analytes, alcoholic modifiers, and acidic/basic additives on its separation performances have been studied in detail. This work expands potential applications of cyclodextrin CSPs in normal modes.
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