Abstract

Bacillus thuringiensis is an aerobic endospore-forming saprophyte that is characterized by the formation of proteinaceous crystalline parasporal inclusions. The organism is a member of the Bacillus cereus group, commonly occurring in soil and phylloplane. B. thuringiensis populations in these environments are highly heterogeneous in many respects. For instance, a variety of H-serotypes occur in both environments. Also, there is a great variation in specificities of parasporal inclusion protein toxicities, providing unique activities preferentially killing insects, nematodes, protozoa or human cancer cells. It is noteworthy that the majority of naturally occurring B. thuringiensis strains produce parasporal inclusion proteins with orphan biological activities.

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