Abstract
The study reports the effects of Bacillus subtilis 29784 on broiler performance. A total of 1,600 one-day-old Cobb 500 male broiler chicks received either a control diet or the same diet to which B. subtilis 29784 spores were added (1E8 CFU/kg of feed). The birds were slaughtered at 42 D of age. Ileal and cecal tissues and content were collected for histomorphological analysis and 16S rRNA gene sequencing, respectively. The inclusion of B. subtilis 29784 led to an increase of final body weight gain of broilers (+5.7%; P < 0.0001) and an improvement in feed conversion ratio (-5.4%; P < 0.0001). Higher feed efficiency in the Bacillus-fed group was correlated with a significant increase in intestinal microvilli length (+18% in ileum and +17% in cecum; P < 0.001). Among the differences revealed by 16S rRNA analysis, Ruminococcus, Lachnoclostridium, and Anaerostipes were found in higher relative abundance in Bacillus-treated birds at the cecal level. These bacterial genera include species that produce butyrate, the main source of energy for enterocytes and known to be an immune modulator. There was also a slight increase in the Butyrivibrio genus in the cecum, which is known to be an important player in the production of conjugated linoleic acid, also considered an anti-inflammatory compound. In conclusion, dietary supplementation of B. subtilis 29784 significantly improved the growth performance of broilers, likely through beneficial effects on microbiota and host.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.