Abstract
The phenomenon here reported was first observed in the course of an unsuccessful attempt to discover among a number of specimens of B. coli bacteriophage one that would be active upon B. pyocyaneus. Of 25 filtrates showing marked lysis of one or more strains of B. coli none could be demonstrated to have any lytic power for any of the 7 strains of B. pyocyaneus tested. The bacteriophage specimens were obtained from the following sources: sewage 4; urine 7; feces 15; pus 2; unknown source 1. The phages were tested on the pyocyaneus cultures both as fresh filtrates and after their lytic power for B. coli had been materially enhanced by repeated passage. Neither clearing of young broth cultures nor plaque formation could be demonstrated with any of the strains of B. pyocyaneus.An attempt was then made with one bacteriophage specimen to bring about pyocyaneus lysis by serial passages upon cultures of the latter organism. A filtrate having marked lytic activity on several strains of B. coli was chosen for this ...
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