Abstract

Early detection of subclinical AF can help prevent significant complications such as embolic stroke, heart failure, and AF-related hospitalizations. We evaluated the performance of a facial pulsation detection video technology called videoplethysmography (VPG) to detect the presence of AF using a monitoring method that does not require a dedicated sensor and/or cumbersome recording procedures. We enrolled patients with AF undergoing either cardioversion or ablation therapy. Patients were asked to collect two 25-sec video recordings daily using a smart tablet loaded with the VPG technology. Early recurrence of AF during the 15-day follow-up period was based on continuous ECG recording (14-day patch monitor). ECGs were manually annotated for the presence of AF episodes lasting >15-sec in duration. The VPG algorithm measured pulse irregularity and was designed to minimize false positive detections. Development and validation were performed on independent datasets (½ split without a subject in common). We report the specificity, sensitivity, and accuracy of the video-based method to detect early recurrence of AF during the follow-up period. The motion of the patient's face was tracked, but no feedback was provided to the subjects during the measurement. We enrolled 112 patients (age: 65∓9 years, 81 men) over an 18 month period. Five subjects did not collect any quality data while 107 patients collected 7∓5 minutes of data on average at home (min:30sec, max: 25min) over 12∓3 days (min:1.5, max:14.7 days). Thirty subjects (28%) experienced at least one 15-sec AF episode post-procedure. The sensitivity and specificity of the AF detection algorithm based on a total duration of 7 min. of video recordings, over 12 days were 33% and 95% in the validation dataset (accuracy: 74%). Less than one-minute daily monitoring using a contactless VPG method can detect AF in one-third of patients experiencing an early recurrence of AF with a 5% false-positive rate. The sensitivity of the VPG method is expected to increase with a larger number of daily VPG recordings.

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