Abstract
B-Lymphoblastic Lymphoma (B-LBL) is a malignancy of immature B lymphoid cells. They have a low propensity for bone marrow involvement. They typically present as generalised lymphadenopathy, bone lesions, mediastinal or skin lesions. They present with more skin and soft tissue involvement than acute lymphatic leukaemias. They are treated with systemic chemotherapy similar to their leukaemic counterparts. They have a favourable prognosis with a survival of 90%, although it worsens with age. Here, we present the case of a 23-year-old gentleman who was evaluated for a swelling in the posterior aspect of right thigh clinically resembling a sarcoma. Imaging studies showed a lesion in the posterior compartment of right thigh which showed contrast enhancement and hyperintensity in T2 images. Pelvic and inguinal node was enlarged. Ultrasound guided biopsy from the lymph node was suggestive of B-LBL. There was no bone marrow involvement. He was treated according to Berlin-Frankfurt-Munster (BFM) 95 protocol and attained remission post induction. He completed induction, consolidation and reinduction and is currently on maintenance treatment.
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