Abstract
B₁₂-deficiency anemia (megaloblastic anemia, pernicious anemia, Addison-Birmer disease), characterized by progressive hyperchromic, macrocytic anemia, hypersegmentation of neutrophil nuclei, megaloblastic erythropoiesis and morphological abnormalities of other hematopoietic growths in the bone marrow; Unlike other anemias, B₁₂-deficiency anemia is often associated with the development of pathological psycho-neurological symptoms (funicular myelosis).This article deals with problems of etiology, pathogeny, clinical symptomatology, approaches to detection and treatment of B₁₂-deficiency anemia.
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