Abstract

Intramolecular Prins reaction of the 2-(2,2-dimethoxyethylamino)-3-(3-methyl-2-butenyl)-1,4-dihydro-1,4-naphthalene-6,11-dione, an amino derivative of lapachol, under hydrolytic conditions, yielded novel azepines condensed with the naphthoquinone nucleus of lapachol.

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