Azalomycin F 4a 2-ethylpentyl ester, a new macrocyclic lactone, from mangrove actinomycete Streptomyces sp. 211726

Gan Jun Yuan,Kui Hong,Hai Peng Lin,Jia Li

doi:10.1016/j.cclet.2010.03.025

Azalomycin F 4a 2-ethylpentyl ester, a new macrocyclic lactone, from mangrove actinomycete Streptomyces sp. 211726

Gan Jun Yuan, Kui Hong + Show 2 more

https://doi.org/10.1016/j.cclet.2010.03.025

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Journal: Chinese chemical letters = Zhongguo hua xue kuai bao	Publication Date: May 31, 2010
Citations: 9

Affiliation: China Medical University, Chinese Academy of Tropical Agricultural Sciences, Shanghai Institute of Materia Medica

#Basis Of Spectroscopic Data #Moderate Cytotoxicity + Show 8 more

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Abstract

Azalomycin F 4a 2-ethylpentyl ester, a new 36-membered macrocyclic lactone antibiotic, was isolated from mangrove actinomycete Streptomyces sp. 211726. Its structure was elucidated on the basis of spectroscopic data. The compound showed broad-spectrum antifungal activity and moderate cytotoxicity against human colon tumor cell HCT-116.

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