Abstract
In adult rats, autologous segments of the peroneal nerve were implanted into the medulla oblongata at the level of the obex either on the midline (midline grafts, n = 4), where respiratory axons decussate, or on the left side (lateral grafts, n = 5) in the area of the respiratory cell bodies. Several months after the graft implantation, spontaneous unitary activities ( n = 225) were recorded within the grafts and were found to arise from both central respiratory (R, n = 72) and non-respiratory (NR, n = 153) neurons which were giving off regenerated axons along the nerve grafts. The graft reinnervation by respiratory axons was found to be significantly more abundant within the medullary lateral grafts than within the midline grafts. This finding offers further support for the conclusion that the reinnervation of grafts by axons from central neurons is enhanced when the graft is placed proximally to the cell bodies.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
