Abstract
BackgroundThe diagnosis of diabetes has important clinic implications for the prevention and management of cardiometabolic disorders. We aimed to investigate the awareness, treatment and control of hypertension and dyslipidemia in previously-diagnosed and newly-diagnosed diabetes in Chinese adult population.MethodsWe conducted a cross-sectional survey in a nationally representative sample of 98658 Chinese adults aged 18 years or older in 2010, using a complex, multistage, probability sampling design. Glycemic status were defined according to the 2010 American Diabetes Association criteria. Hypertension was diagnosed by the Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. Dyslipidemia was diagnosed by the 2004 National Cholesterol Education Program Adult Treatment Panel III.ResultsThe weighted prevalence of hypertension and dyslipidemia gradually increased in adults with normal glucose regulation, prediabetes, newly-diagnosed diabetes and previously-diagnosed diabetes. Compared to newly-diagnosed diabetes patients, previously-diagnosed diabetes patients were more likely to be aware of hypertension (weighted percentage [95% confidence interval]: 55.2% [52.9%-57.5%] vs 37.6% [35.9%-39.3%]) and dyslipidemia (33.9% [31.8%-36.1%] vs 12.8% [11.7%-13.9%]), to receive blood pressure-lowing (43.7% [41.5%-46.0%] vs 27.5% [26.0%-29.0%]) and lipid-lowering (18.9% [17.2%-20.7%] vs 5.4% [4.6%-6.2%]) therapies, and to have controlled blood pressure (4.7% [3.5%-6.2%] vs 3.5% [2.6%-4.8%]) and lipid (15.9% [12.3%-20.3%] vs 9.5% [6.4%-13.8%]) levels.ConclusionsDetection and control of hypertension and dyslipidemia is far from optimal in Chinese adults, especially in newly-diagnosed diabetes. Improved screening for diabetes is required to promote a better prevention, treatment and control of hypertension and dyslipidemia in China.Electronic supplementary materialThe online version of this article (doi:10.1186/s12933-015-0191-6) contains supplementary material, which is available to authorized users.
Highlights
The diagnosis of diabetes has important clinic implications for the prevention and management of cardiometabolic disorders
The China Noncommunicable Disease Surveillance 2010 is a nationally representative study [12], in which we have reported that 11.6% of Chinese adults aged 18 years or older had diabetes in 2010, while less than one-third (30.3%) of diabetes patients were aware of their condition [12]
Our data suggested that diabetes have reached an alert level in China, with the potential for a major epidemic of diabetes-related metabolic disorders, such as hypertension and dyslipidemia, which act as independent contributors to cardiovascular disease especially in patients with diabetes [13,14,15]
Summary
The diagnosis of diabetes has important clinic implications for the prevention and management of cardiometabolic disorders. We aimed to investigate the awareness, treatment and control of hypertension and dyslipidemia in previously-diagnosed and newly-diagnosed diabetes in Chinese adult population. Our data suggested that diabetes have reached an alert level in China, with the potential for a major epidemic of diabetes-related metabolic disorders, such as hypertension and dyslipidemia, which act as independent contributors to cardiovascular disease especially in patients with diabetes [13,14,15]. Data from the United States National Health and Nutrition Examination Survey (NHANES) have revealed that newly-diagnosed diabetes was associated with a lack of awareness, treatment and control of high low-density lipoprotein cholesterol (LDL-C) [17]. There are limited data concentrated on the awareness, treatment and control of hypertension and dyslipidemia in previously-diagnosed diabetes versus newly-diagnosed diabetes
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