Abstract

BackgroundType 2 diabetes is an escalating public health problem in Nepal. The current study aims to assess the prevalence, associated factors, awareness, treatment, and control of type 2 diabetes in a semi-urban area of Nepal.MethodsA population-based cross-sectional survey was conducted including 2,310 adults aged 25 years or above from a semi-urban area of Lekhnath Municipality of Nepal, during October 2016 to April 2017 using the World Health Organization (WHO) STEPS approach. Data on demographics, behavioral risk factors, blood pressure, anthropometric measurements (weight, height, waist and hip circumference), and fasting blood glucose were collected by face-to-face interviews during a door-to-door visit. Participants were considered to have type 2 diabetes if they had previously been diagnosed by a physician and/or were on antidiabetic medications and/or had fasting blood glucose ≥ 7.0 mmol/L. Participants were classified as being aware of their diabetes conditions if they had earlier been told that they had type 2 diabetes. Treatment of diabetes among those aware was if participants received any kind of medication treatment or counseling, and control of diabetes among those treated was defined as fasting blood glucose level was <7.0 mmol/L. Odds Ratio (OR) with 95% Confidence Interval (CI) was used to determine the strength of association.ResultsThe prevalence of type 2 diabetes was 11.7% (95% CI: 10.5–13.1). Among type 2 diabetes participants, 65% were aware of their disease, 94% of those who were aware received treatment, and 21% of the treated subjects had their diabetes under control. Factors significantly associated with type 2 diabetes were older age (OR = 3.2 for age group 45–54 years, OR = 3.8 for age group 55–64 years), Janajati ethnicity (OR = 1.4), abdominal obesity (OR = 2.3), being overweight or obese (OR = 1.4), and hypertension (OR = 2.0), while protective factors included being a female (OR = 0.4), medium physical activity (OR = 0.3), high physical activity (OR = 0.2), and not having family history of diabetes (OR = 0.3).ConclusionsThe study revealed a high prevalence of type 2 diabetes among adults. Older age, male gender, Janajati ethnicity, abdominal obesity, overweight or obesity, hypertension, low physical activity, and family history of diabetes were associated with type 2 diabetes. Immediate public health and individual measures are warranted to reduce further burden of type 2 diabetes.

Highlights

  • Global estimates of diabetes prevalence in 2014 suggested that the number of people with type 2 diabetes was 422 million and this number is projected to increase to 642 million by 2035 [1]

  • Treatment of diabetes among those aware was if participants received any kind of medication treatment or counseling, and control of diabetes among those treated was defined as fasting blood glucose level was

  • The prevalence of type 2 diabetes was 11.7%

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Summary

Introduction

Global estimates of diabetes prevalence in 2014 suggested that the number of people with type 2 diabetes was 422 million and this number is projected to increase to 642 million by 2035 [1]. There is an increasing trend in the prevalence of type 2 diabetes in low-and middle-income countries (LMICs), and more than 75% adults with type 2 diabetes are living in developing countries [1]. South Asia is experiencing an increasing burden of type 2 diabetes and its complications [3]. One-fifth of all adults with type 2 diabetes in the world live in the South-East Asia Region. A 2015 systematic review and meta-analysis estimated that the prevalence of type 2 diabetes in Nepal was 8.4% (95% CI: 6.2–10.5%) [4], but the quality of the included studies were generally low, and results may not be representative for the population of Nepal as a whole. The current study aims to assess the prevalence, associated factors, awareness, treatment, and control of type 2 diabetes in a semi-urban area of Nepal

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