AW-AD-3: ATRIAL FIBRILLATION AS PREDICTOR OF MORTALITY IN HEMODIALYSIS PATIENTS WITH CARDIOVASCULAR DISEASE

Abstract

Background: The predictors of mortality in hemodialysis patients remain unknown, especially in patients with cardiovascular disease. Aim: To find the predictor of mortality in hemodialysis patients with cardiovascular disease. Methods: A number of 444 hemodialysis patients with cardiovascular disease in 2018 participated in the study. We performed history taking to determine comorbid (history and duration of hypertension, history of diabetes, coronary artery disease, congestive heart failure, stroke, vascular disease, liver disease, and alcohol consumption) and electrocardiography as baseline data. The patients then were followed up to assess the death event. Cox proportional hazards models were used to estimate hazard ratios (HR) and their 95% CI for various covariates. Results: Among 444 hemodialysis patients, 266 patients matched the inclusion and exclusion criteria, 166 patients were completely followed up in December 2019. The mean age was 50.8 ± 14.68 years, 52.4% female, mean duration of follow-up duration was 11.2 ± 10.08 months. History of hypertension was found in 149 (89.8%) patients. We observed all-cause death in 109 patients (65.7%) patients. Hypertension, diabetes, coronary artery disease, congestive heart failure, stroke, and vascular disease were not associated to death. We found out that atrial fibrillation was associated as a predictor of death (HR 2.540; 95% CI, 1.558–4.140, p = <0.001). Conclusions: Atrial fibrillation was associated with a higher incidence of death in hemodialysis patients with cardiovascular disease.