Abstract
In April 2017, three avian influenza (H7N9) viruses were isolated from chickens in southern China. Each virus had different insertion points in the cleavage site of the hemagglutinin protein compared to the first identified H7N9 virus. We determined that these viruses were double or triple reassortant viruses.
Highlights
During 2016–2017, three avian influenza A(H7N9) viruses were isolated from chickens in southern China
According to reports of H7N9 virus outbreaks among humans in China, the virus clustered into the Yangtze River Delta lineage and the Pearl River Delta lineage (2)
Q26 and Q39 had 4 continuous basic amino acids at cleavage sites (KRKRTARG), which is a characteristic of highly pathogenic avian influenza virus (Online Technical Appendix, Table 1, https://wwwnc.cdc.gov/EID/article/23/12/17-0782Techapp1.pdf)
Summary
During 2016–2017, three avian influenza A(H7N9) viruses were isolated from chickens in southern China. Since its first documentation on March 30, 2013, through March 16, 2017, avian influenza A(H7N9) virus has caused 5 epidemic waves of infection among humans in China, resulting in 1,307 laboratory-confirmed clinical cases and 489 deaths (1). According to reports of H7N9 virus outbreaks among humans in China, the virus clustered into the Yangtze River Delta lineage and the Pearl River Delta lineage (2).
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