Abstract
The effects of steroids on the skeleton have been described extensively, and it is not surprising that most of the information regarding joint changes in this context has been obtained from the study of the effects of steroids on rheumatoid disease or osteoarthritis. In these conditions it is of some interest that cortisone and its analogues may sometimes appear to hasten a destructive process, especially in weight-bearing joints such as the hip (Ansell, 1958; Chandler and Wright, 1958; Chandler, Jones, Wright and Hartfall, 1959; Murray, 1960; 1961; Sweetnam, 1960). It is felt that this type of joint lesion must be distinguished clearly from avascular necrosis of bone occurring in association with steroid therapy in patients without evidence of previous arthropathy. Prior to 1963 few examples of such a condition were recorded. Four cases were described by Heimann and Freiberger (1960), two of their patients showing changes in both the femoral and humeral heads. One case, also with hips and shoulders affec...
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