Abstract

Objective: The present ex vivo study aimed to assess the apical sealing ability of the endodontic sealer MTA FILLAPEX® compared to Sealapex, Pulp Canal Sealer, and AH26. Methods: The ability to prevent leakage of a culture of Enterococcus faecalis through the root canal obturation was assessed. Forty-eight single-rooted teeth that had been extracted from humans were used. Following instrumentation and obturation using the warm gutta-percha vertical condensation technique, the teeth were allocated into one of four experimental groups (n=10), a positive control group (n=4), or a negative control group (n=4). The microbial inoculation was performed every three days over 60 days. The data were tabulated and subjected to statistical survival analysis, whereby the performance of the four investigated sealers was compared using the log-rank test. Results: The results revealed that all of the samples in the group in which MTA FILLAPEX® was used exhibited leakage. Sealapex and Pulp Canal Sealer exhibited leakage in 90 and 80% of the samples, respectively. The sealer AH26 was significantly superior in delaying leakage, although 30% of the samples exhibited leakage. Conclusion: MTA FILLAPEX® permitted the most Enterococcus faecalis leakage compared to the other investigated sealers.

Highlights

  • In all areas of dentistry, explanations for observations that are not fully understood are tirelessly sought to improve knowledge, techniques, and the materials that are used in clinical practice

  • When strictly anaerobic techniques are applied to endodontic cultures, many infections that were formerly caused by aerobic or facultative bacteria are classified as polymicrobial infections, where anaerobic bacteria are prevalent

  • The success of endodontic treatment depends on the attention that is given during all stages, i.e., from when the medical history is obtained through follow-up, three-dimensional hermetic obturation of the root canal system (RCS) is a crucial step [2]

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Summary

Introduction

In all areas of dentistry, explanations for observations that are not fully understood are tirelessly sought to improve knowledge, techniques, and the materials that are used in clinical practice. The primary aim of endodontic therapy is to prevent and treat periradicular inflammation by eliminating microorganisms from the root canal system (RCS). Modern endodontic therapy follows basic principles that are grounded on wellstructured scientific foundations that guide all of the stages of treatment. The success of endodontic treatment depends on the attention that is given during all stages, i.e., from when the medical history is obtained through follow-up, three-dimensional hermetic obturation of the RCS is a crucial step [2]. Such obturation prevents the percolation and microleakage of the periapical exudate into the internal canal space, hindering reinfection. Obturation promotes an environment that is biologically favorable to the tissue healing

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