Abstract
The present study aimed to evaluate the occurrence of metabolic alterations and suppression of thyroid hormones after topical treatment with 0.0584% hydrocortisone aceponate in dogs with localized allergic dermatitis. The sample consisted of ten dogs (four females and six males, mean age 6.5 ± 4.4 years). A 30-day therapy with hydrocortisone aceponate was initiated. The drug was used once daily for seven days, and subsequently three times a week for three weeks. Several laboratory tests were performed before and after treatment (ALT, AF, triglycerides, cholesterol, glycemia, fructosamine, serum insulin, free T4 by equilibrium dialysis and canine TSH) and the results showed no statistically significant difference. We concluded that the protocol used was safe in our sample. Even when used for longer than the time recommended by the manufacturer, the drug caused no observable adverse metabolic effects.
Published Version
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