Abstract
The humoral immune response of cattle vaccinated with inactivated bovine viral diarrhea virus (BVDV) using the association of dimethyl dioctadecyl ammonium chloride (DDA-chloride) and aluminum hydroxide (vaccine B) as adjuvant, was compared with the same antigenic formulation adsorbed with only aluminum hydroxide (vaccine A). The neutralizing antibodies titers were assessed two weeks after the second vaccine dose. The animals that received vaccine B had better humoral responses than the calves vaccinated with vaccine A. The mean titers of neutralizing antibodies, expressed in Log2, for the calves that received vaccine B was higher to those observed in group vaccinated with vaccine A. These results show that the inclusion of DDA chloride in vaccine formulations adsorbed with aluminum hydroxide determine a better humoral immune response in cattle vaccinated with BVDV inactivated.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Brazilian Journal of Veterinary Research and Animal Science
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
