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Abstract
Summary and ConclusionsAfter intramuscular injection of staphylococcal antitoxin the rate of absorption is quite uniform in normal monkeys and humans. The antibody available in the total plasma-volume during a given period of days after injection of a specified dose (per kg weight) may be determined from the area under the curve, formed with time intervals as abscissae and daily concentrations of antibody per cc as ordinates, multiplied by the plasma volume. This new method of calculating available circulating antibody has also been applied successfully to the data of Glenny and Hopkins3 on diphtheric antitoxin and hence may be of general im-munological interest.
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