Abstract
In an incidence study of chromosome abnormalities among 5049 consecutive liveborn children at a Danish maternity hospital we found 43 with major chromosome abnormalities; 7 had a balanced reciprocal autosomal translocation. Segregation rate in the families of the 6 cases, who were inherited, showed no significant deviation from unity between carriers of balanced translocations and individuals with normal chromosome constitution. The sex distribution of carriers and those with normal chromosome constitution was normal, and segregation and distribution between carriers and non-carriers was independent of whether the carrier was a male or a female.
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