Abstract

BackgroundThe study of the seasonal variation of disease is receiving increasing attention from health researchers. Available statistical tests for seasonality typically indicate the presence or absence of statistically significant seasonality but do not provide a meaningful measure of its strength.MethodsWe propose the coefficient of determination of the autoregressive regression model fitted to the data () as a measure for quantifying the strength of the seasonality. The performance of the proposed statistic is assessed through a simulation study and using two data sets known to demonstrate statistically significant seasonality: atrial fibrillation and asthma hospitalizations in Ontario, Canada.ResultsThe simulation results showed the power of the in adequately quantifying the strength of the seasonality of the simulated observations for all models. In the atrial fibrillation and asthma datasets, while the statistical tests such as Bartlett's Kolmogorov-Smirnov (BKS) and Fisher's Kappa support statistical evidence of seasonality for both, the quantifies the strength of that seasonality. Corroborating the visual evidence that asthma is more conspicuously seasonal than atrial fibrillation, the calculated for atrial fibrillation indicates a weak to moderate seasonality ( = 0.44, 0.28 and 0.45 for both genders, males and females respectively), whereas for asthma, it indicates a strong seasonality ( = 0.82, 0.78 and 0.82 for both genders, male and female respectively).ConclusionsFor the purposes of health services research, evidence of the statistical presence of seasonality is insufficient to determine the etiologic, clinical and policy relevance of findings. Measurement of the strength of the seasonal effect, as can be determined using the technique, is also important in order to provide a robust sense of seasonality.

Highlights

  • The study of the seasonal variation of disease is receiving increasing attention from health researchers

  • Measurement of the strength of the seasonal effect, as can be determined using the R2Autoreg technique, is important in order to provide a robust sense of seasonality

  • Several statistical tests have been introduced for studying the cyclical variation of time series data

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Summary

Introduction

The study of the seasonal variation of disease is receiving increasing attention from health researchers. Available statistical tests for seasonality typically indicate the presence or absence of statistically significant seasonality but do not provide a meaningful measure of its strength. Several statistical methods are available ranging from simple graphical techniques to more advanced statistical methods. Several statistical tests have been introduced for studying the cyclical variation of time series data. Edwards [1] developed a statistical test that locates weights corresponding to the number of observed cases for each month at 12 spaced points on a circle. Jones et al [2] developed a test for determining whether incidence data for two or more groups have the same seasonal pattern. To apply any of these tests, observations must be aggregated into 12 monthly data points

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