Abstract

After injection of 14C-labelled DOPA following pretreatment with a peripheral L-DOPA decarboxylase inhibitor, Ro-4-4602 in mongolian gerbils, retention of radioactivity occurs in dopaminergic brain areas, the pancreas, epididymus and hair follicles. Labelling of the dopaminergic brain structures is maximal 1 hr after injection of DOPA.

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