Abstract
The morphological distribution of acetylcholine receptors in the whole biceps brachii muscle from a patient with amyotrophic lateral sclerosis (ALS) and from a control patient was studied by in vitro autoradiography with 3H-alpha-bungarotoxin (alpha-Btx). In ALS, 3H-alpha-Btx binding occurred over the entire muscle, while in the control case the binding was restricted to the motor end-plate region.
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