Abstract
The amount of DNA and RNA, and the rate of orotic 14C-6-acid incorporation into these nucleic acids in tadpole liver do not change during thyroxine-induced metamorphosis. However, autoradiographic studies on liver with 3H-thymidine revealed that thyroxine treatment increased the number of liver cells in DNA synthesis. On the other hand, 3H-thymidine incorporation into nuclei of tail cells was not affected. Evidence is also presented to indicate that tadpole liver contains cytoplasmic DNA which incorporated the 3H-thymidine twice as fast as nuclear DNA.
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