Abstract

PO-350 Autophagy and mTOR inhibition as mechanisms for combatting chemoresistance to standard chemotherapy: Final results of a phase I study of infusional cyclophosphamide (cy), pulse dexamethasone (dex), rapamycin (rapa) and hydroxychloroquine (HCQ) E.C. Scott, S. Reasor-Heard, K. Floyd, B. Park, P. Trubowitz, E. Medvedova, S.E. Spurgeon, S.D. Smith, A. Kratz, M. Gordon, M. Siegel, S.Q. Liu, R. Arora, M. Loriaux, E. Stadtmauer, R. Amaravadi, D.T. Vogl, R.T. Maziarz The Knight Cancer Institute, Oregon Health and Science University; The Abramson Cancer Center, the University of Pennsylvania

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